1. An isolated population of chimpanzees was discovered on anisland. Biochemical studies show that 1 out of 9 chimpanzees inthis population are homozygous for a mutation in the gene encodingthe enzyme, hexokinase. This mutation completely inactivates theenzyme so that no activity is detected in the blood. A female whoexhibits hexokinase activity mates with a male who is a carrier ofthe hexokinase mutation. What is the probability that their firstbaby chimpanzee will be homozygous for the hexokinase mutation?Assume that the population is in Hardy-Weinberg equilibrium.
2. Cystic fibrosis is an autosomal recessive, fully penetranttrait in humans.Ă‚Â Ă‚Â Ă‚Â Ă‚Â A man who is unaffected bycystic fibrosis has two unaffected parents and a sister with cysticfibrosis.Ă‚Â Ă‚Â The man plans to marry a healthy woman, whowas adopted and has no knowledge about her biological parentsexcept that they are both Caucasian. The frequency of cysticfibrosis in the Caucasian population is 1/2500. Assuming that thispopulation is in Hardy-Weinberg equilibrium for the CFgene, what is the probability that this couple's first child willhave cystic fibrosis?
