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1. Glyburide, a member of the sulfonylurea family of drugs, is used to treat type 2...

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Biology

1. Glyburide, a member of the sulfonylurea family of drugs, isused to treat type 2 diabetes. It binds to and closes the ATP-gatedK+ channels on the pancreatic beta cells. This leads to membranedepolarization and activation of voltage-gated Ca2+ channelstriggering fusion of insulin containing vesicles with the plasmamembrane causing subsequent release of insulin into the blood.Given the mechanism of this drug’s action, would you expectglyburide to be useful for treating type I diabetes? Why or whynot? 5 points

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Ans Glyburide also known as glibencamide is an FDA approved sulfonylurea of second generation that is used for the traetment of type 2 diabetes mellitus DM It is available in the form of generic formulation It is    See Answer
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