1. If this insertion is within the coding region of a viralprotein, will this insertion result in a frameshift for the rest ofthe protein? How do you know?
2. The insertion mutation is in a gene that codes for a proteinon the surface of the virus, probably a glycoprotein. Assume thatthis protein is involved in attachment to a host cell. How might achange in a protein involved in attachment change the potentialhosts for the virus?
3. How long does it typically take a person's adaptive immunesystem to make antibodies in a primary response to an antigen? Isit likely that a person would have memory B cells that recognize anew surface protein on the virus? Why or why not?
4. Why is a population unlikely to have herd immunity to a virusthat has a new protein on its surface?
