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List of drugs that can induce sickle cell anemia
2) mechanism of action of sickle cell...
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Medical Sciences
1)List of drugs that can induce sickle cell anemia
2) mechanism of action of sickle cell anemia
3) treatment options for sickle cell anemia
4) describe polycythemia including definition, causes,mechanism and treatment options
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1 Drug induced sickle cell anemia also called drug induced immune haemolytic anemia DIIHAmethyldopa ceftriaxone cefotetan pencillin etc 2 Basic molecular lesion In HbS basic genetic defect is the single point mutation in one amino acid out of 146 in haemoglobin moleculethere is substitution of valine for glutamic acid at 6residue position of the bglobin producing Hb a2b2s Mechanism of sickling During deoxygenation the red cells containing HbS change from biconcave disc shape
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