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1. Specific extracellular signal molecules require a cell surface receptor. What about the chemistry of these signals...

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Biology

1.Specific extracellular signal molecules require a cell surfacereceptor. What about the chemistry of these signals prevents themfrom diffusing across the cell membrane?
2. What is the difference between endocrine signaling,paracrine signaling and autocrine signaling?
3. Why do cellular signal molecules bing to a receptor usingnoncovalent forces rather than a covalent bond?
4. What is the different between kinases and phosphates? Howdo they impact activity of the target protein. Please give anexample that involves kinases and phosphates.
5. How do kinases recognize their substrates and the proteinsthey act on?
6. What is the difference between the active form and inactiveform of GTPase superfamily of proteins?
7. How are second messengers different from firstmessengers?

Answer & Explanation Solved by verified expert
3.7 Ratings (545 Votes)
1 These signal molecules are impermeable to lipid bilayer plasma membrane because of their hydrophilic nature 2 The major difference between the different types of signalling is the distance that the signal travels to reach the target cell Endocrine signalling uses the circulatory system to transport ligands    See Answer
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