1
Variation in what part of the pathway would affect theproduction of each of the melanin pigments? Describe theconsequences of mutations in different parts of the pathway and itseffects on the two melanin pigments.
2
Propose a mechanism by which the C-T nucleotide change in TYRP1gene may have caused the blond hair trait.
3
Using the Hardy-Weinberg equilibrium:
a. What are the observed genotype frequencies in the SolomonIslands?
b. Calculate the blond hair allele frequency and the dark hairfrequency in the Solomon Islands and worldwide.
c. If we assume that the population follows Hardy-Weinbergassumptions, what is the expected frequency of heterozygouscarriers in both populations?
4
How do you think the gene for blond hair was introduced to theislands?