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1. What function of intermediate filaments is lacking in people with epidermolysis bullosa complex? A) what type of...

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Biology

1.What function of intermediate filaments is lacking in people withepidermolysis bullosa complex?

A) what type of intermediate filaments are affected?

2. What type of intermediate filament is affected inProgeria?

3. What is the current hypothesis as to how the loss ofintermediate filaments leads to the excessive and vastly prematureaging?


Answer & Explanation Solved by verified expert
3.9 Ratings (770 Votes)
1 Intermediate Filaments function as stress sensors in tissue cells and function through various mechanisms of remodeling triggered mechanical stress like cell deformation by stretching swelling pressure friction and heat IFs have a role in maintaining mechanical resilience in epithelia and act as a scaffold for maintaining cell and tissue integrity due to unique configuration of keratin filament bundles and desmosome cellcell junctions It is the loss of this function of IFs in    See Answer
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