1-1. Ecstasy or MDMA uses a unique mechanism; it bindsto the serotonin reuptake transporter and does two things. Ecstasystops serotonin reuptake and causes the transporter to reversedirection, moving serotonin from the synaptic terminal into thesynapse. Due to this mechanism, what effect will ecstasy have onpostsynaptic neurons? (Include in your answer whether EPSP or IPSPis affected.)
1-2. The pharmaceutical company is looking to introducea new drug that enhances neurotransmission. Knowing what you knowabout the physiology of neurotransmission, the company is askingyou what part of the pathway you would recommend targeting and howthat would enhance neurotransmission. Explain how your drug wouldwork and what part of neurotransmission your drug wouldtarget.
