4. Under each of the following conditions, please predict theeffect the mutation will have on the rate at which glycolysis willproceed in liver cells:
a. Loss of the allosteric site for ATP inphosphofructokinase
b. Loss of binding site for citrate in phosphofructokinase
c. Loss of the phosphatase domain of the bifunctional enzymethat controls the level of fructose 2,6-bisphosphate
d. Loss of the binding site for fructose 1,6-bisphosphate inpyruvate kinase.