A cell that is synthesizing insulin is lacking Signal
Recognition Particle (SRP) receptors at the level...
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Biology
A cell that is synthesizing insulin is lacking SignalRecognition Particle (SRP) receptors at the level of the roughendoplasmic reticulum. In your own words,describe the impact, if any, on the synthesis andsecretion (exocytosis) of insulin from the cell. Explainyour answer..
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Insulin is a hormone that regulates blood glucose levels in humans It is synthesized and secreted by the beta cells of Islets of Langerhans of the pancreas The mRNA is translated on ribosomes of rough endoplasmic reticulum RER as a single chain precursor This precursor is called preproinsulin 110kDa Preproinsulin has a signal peptide that causes its insertion into the endoplasmic reticulum This insertion generates the proinsulin molecule The insertion of preproinsulin into ER to form proinsulin requires the N terminal signal peptide in preproinsulin This N terminal
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