For Drug A and protein complex
    Â
        DrugA +
protein         Â
-->Â Â DrugA -protein
Initial   a   b
            Â
0
Final   a-x     b-x x
 Â
Kc = equilibrium constant = x /(a-x)(b-x)
Kc = 1.00×10−6 / 1.00×10−6 X 0.78 X 10^-6
Kc = 1.28 X 10^6
For Drug A and protein complex  Â
        Drug B +
protein --> DrugB -protein
Initial   a   b
            Â
0
Final   a-x     b-x x
 Â
Kc = equilibrium constant = x /(a-x)(b-x)
x = 1.4×10−6
a = 2.00×10−6M
b = 1.78×10−6
a-x = 0.6×10−6
b-x = 0.38 X 10^-6
Kc = 1.4×10−6 / 0.6×10−6 X 0.38 X 10^-6
Kc = 6.14 X 10^6
