A chemist at a pharmaceutical company is measuring equilibriumconstants for reactions in which drug candidate molecules bind to aprotein involved in cancer. The drug molecules bind the protein ina 1:1 ratio to form a drug-protein complex. The proteinconcentration in aqueous solution at 25 ∘C is 1.58×10−6M . Drug A is introduced into the protein solution at an initialconcentration of 2.00×10-6 M. Drug B is introduced intoa separate, identical protein solution at an initial concentrationof 2.00×10-6 M. At equilibrium, the drug A-proteinsolution has an A-protein complex concentration of1.00×10-6 M, and the drug B solution has a B-proteincomplex concentration of 1.40×10-6 M.
Part A: Calculate the Kc value for the A-proteinbiding reaction.
Part B: Calculate the Kc value for the B-proteinbiding reaction.
Part C: Assuming that the drug that binds more strongly will bemore effective, which drug is the better choice for furtherresearch?
