A child has severe intellectual disability, developmental delay,autism and unusual facial features, His mother had a learningdisability and slightly delayed development. Genome sequencing aswell as karyotyping reveal that the child has excess material fromchromosome 9 and 14 and too little from chromosome 10. Th motherhas all of the genetic material, but she has four “derivative”chromosomes – they have seemingly mixed and matched their parts.These chromosomes consist of pieces of 9, 10, and 14; 9, 10, and16; and 9 and 4.
a. What chromosomal event has likely occurred?
b. How can the nature of the chromosomal event explain the mother’slearning disability and developmental delay, but good healthotherwise and a full genome?
