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A couple is having difficulty conceiving a baby. After various tests, it was found that the...

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Medical Sciences

A couple is having difficulty conceiving a baby. After varioustests, it was found that the woman cannot ovulate. Describeendocrine alterations that could explain why she cannot ovulate.Ensure that you describe relevant tissues and feedback mechanismsin your answer.

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Anovulation is when the ovaries do not release an oocyte during a menstrual cycle Therefore ovulation does not take place However a woman who does not ovulate at each menstrual cycle is not necessarily going through menopause Chronic anovulation is a common cause of infertility To understand anovulation you first understand what occurs during a normal ovulatory cycle In normal physiology ovulation is dependent on the presence of a functioning hypothalamicpituitaryovarian HPO axis The arcuate nucleus within the hypothalamus is composed of a collection of neurons and when stimulated releases GnRH into the portal vessels of the pituitary stalk in a pulsatile fashion GnRH stimulates receptors in the anterior pituitary gland to produce and secrete both LH and FSH In women FSH induces maturation of ovarian follicles and eventual production of estrogen while LH    See Answer
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