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A pharmacy student is testing six different drugs that target neuromuscular transmission. Predict if the following...

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Medical Sciences

A pharmacy student is testing six different drugs that targetneuromuscular transmission. Predict if the following drugs wouldincrease, decrease or not change the magnitude of the end platepotential at the neuromuscular junction.

Acetylcholinesterase inhibitor

      [ Choose ]           No change           Increase           Decrease      

Botulism toxin

      [ Choose ]           No change           Increase           Decrease      

Black widow latrotoxin

      [ Choose ]           No change           Increase           Decrease      

Antagonist of presynaptic voltage-gated Ca2+ channels

      [ Choose ]           No change           Increase           Decrease      

Antagonist of Ach receptors

      [ Choose ]           No change           Increase           Decrease      

Antagonist of sarcolemmal voltage-gated Na+ channels

[ Choose ]            Nochange           Increase           Decrease

Answer & Explanation Solved by verified expert
4.4 Ratings (785 Votes)
1Acetylcholinesterase InhibitorsIncrease Endplate potentials Acetyl choline inhibitors are the drugs that inhibit Acetylcholinesterasewhich degrade AcetylcholineSo it increases concentration of Acetyl choline which increases levels of Acetyl choline binding to post synaptic membrane which increase Endplate    See Answer
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