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A study is conducted on 8,000 individuals free of diabetes and 8,000 individuals with diabetes. The...

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Biology

A study is conducted on 8,000 individuals free of diabetes and8,000 individuals with diabetes. The investigators are looking todetermine if a newly marketed drug may prevent diabetes. Amongpatients with diabetes, 1,000 individuals received the new drug.Among patients without diabetes, 2,000 individuals received thedrug.

4a. Construct a 2 by 2 tabledisplaying the combination of diabetics/non-diabetics who areexposed/not exposed.

4b. Calculate an odds ratio andprovide an interpretation

4c. Calculate the relative risk andprovide an interpretation.

4d. If the number of non-diabeticpatients was increased to 800,000, would you expect the answers in2b and 2c to be more or less similar to each other? Explainwhy.

Answer & Explanation Solved by verified expert
3.9 Ratings (653 Votes)
4aDIABETICNONDIABETICExposed10002000Not exposed700060004b Odd ratio OR is used to measure the relationship betweenthe exposure and its possible outcomes mainly in case of certaincase studies clinical trial of drugs etc It is calculated toobserve the effect of one situation in the presence or absence ofanother situationIt is calculated as followsOdds for Diabetic    See Answer
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