a. What are the steps/characteristics of lysosome centeredprotein degradation? Discuss any specificities and give an exampleof at least one protein which is cleared via the lysosomaldegradation.
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b. What are the steps in the proteasome centered proteindegradation via ubiquitination? Include the labeling with ubiquitinand the steps in proteasome and post proteasome processing. Discussany specificities and give an example of at least one protein whichis degraded via ubiquitination and the proteasome.
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iv) Protein degradation may also be a way of regulating enzymeactivities. What is an example of regulation of a key enzyme of apathway where a product or effector regulates enzyme activity byincreasing or decreasing the rate of degradation of the enzymeprotein?
