After returning to the recovery room the valve starts to leakand the blood pressure starts to fall, a patient who was sentopen-heart surgery for a replacement of an aortic valve. After thepersonal starts to infuse norepinephrine to increase the bloodpressure, the renal function of the patient starts to decline.
1. What are the mechanisms by which norepinephrine might lowerthe glomerular filtration rate? Be sure to focus on renal plasmaflow and Glomerular Capillary Hydrostatic Pressure.
2. The personal is concerned by his lowered glomerularfiltration rate. The elect to try a new treatment, the infusion ofatrial natriuretic peptide (ANP). What might be the mechanism bywhich this would increase GFR?
