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Anders and Ben are brothers Ben has cystic fibrosis and Anders does not The gene...

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Anders and Ben are brothers Ben has cystic fibrosis and Anders does not The gene that when mutated causes cystic fibrosis is called CTFR The beginning of the CFTR DNA coding sequence is shown for each brother The reading frame begins with the start codon Met What type of mutation causes Ben s cystic fibrosis Consult a codon table Anders 5 TCGATGAACGGTCTA Ben 5 TCGATGAACGATCTA O Missense O Frameshift O Silent 3 3

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