Andre the Giant had a somatotropinoma, which is a tumor thatsecretes too much hormone on it’s own (without the need of outsidestimulation). Where would this tumor be located and what hormone isbeing secreted from this tumor (2 pts)? What hormone normallystimulates somatotroph cells (1 pts)? What happens next in thispathway (continue explaining the pathway as if there wasn’t atumor) (5 pts)? What negative feedback should be affecting thesomatotropinoma (3 pts), and why might it not be working (2 pts)?Why is this condition dangerous if not treated (2 pts)? One of thetreatments for this type of tumor is somatostatin (SS), whichactually also affects another pituitary pathway. What pathway alsoresponds to SS, and specifically HOW is that pathway affected (2pts)? Based on this information, what other hormonal disorders canSS be used to treat (note, we’re not asking about treatment of thesomatotropinoma in this question) (1 pt)? 2 pts for essayformatting, grammar, spelling.
