Answer the following questions (a through f) based upon apeptide sequence with the following amino acids (one-letter symbolsare given): EHSGLR
(a) What are the full names and three-letter abbreviations ofthe amino acids?
(b) At physiological pH, what is the best description of thechemical properties of the side chains(R groups)? (Hint: Selectbetween nonpolar, polar uncharged, positively charged, negativelycharged)
(c) Draw the structure of this peptide at pH 7.0.
(d) What is the net charge of the molecule at pH 3, 8, and 11?(Use pKa values for side chains and terminal amino and carboxylgroups as given in Table 3–1.)
(e) Estimate the pI for this peptide.
(f) What type of intermolecular force could the side chains formwith water? (Note that these are interactions are with water, notwith other amino acids.)
