Anthropologists examined the gene for Rh blood type in twovillages on the northern coast of Nunavut, Canada. This blood typehas two alleles, "plus" and "minus". The "plus" allele had afrequency of 60% in Taloyoak, and a frequency of 50% in Kugaaruk.For the remaining part of the question, we will assume that the twovillages have the same population size.
Step 1a: For Taloyoak, what is the frequency of the "minus"allele?
Step 1b: For Kugaaruk, what is the frequency of the "minus"allele?
Step 2a: What is the average allele frequency for "plus" inthe total population including both villages?
Step 2b: What is the average allele frequency of the "minus"allele in the total population including both villages?
Step 3a: What is the heterozygosity in Taloyoak?
Step 3b: What is the heterozygosity in Kugaaruk?
Step 4: What is the average of the heterozygosities inTaloyoak and Kugaaruk (HS)?
Now go back to the average allele frequencies you calculatedin step 2a and 2b.
Step 5: What is the heterozygosity based on the totalpopulation allele frequencies (HT)?
Step 6: Calculate FST = (HT-HS)/HT.
