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Benzodiazepines are positive allosteric modulators at the GABA-A receptor. a) Describe how positive allosteric modulators affect receptor...

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Medical Sciences

Benzodiazepines are positive allosteric modulators at the GABA-Areceptor. a) Describe how positive allosteric modulators affectreceptor function. b) Discuss the mechanism of action ofbenzodiazepines and their effect on central nervous system (CNS)activity. c) GABA is also an agonist at GABA-B receptors,which are G protein coupled receptors that couple to Gi. Explainthe signalling pathways that will be activated when GABA binds tothe GABA-B receptor.

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aAllosteric modulators are group of substance that bind to the receptor to change the receptor response to the stimuliBenzodiazepines like diazepam are positive allosteric modulators at GABAA They    See Answer
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