Case study
8-year old girl with recurrent infections caused byStreptococcus pyogenes and Hemophilus influenza was admitted to thehospital following a 5-day sinus infection. Her mother noted thatshe had developed a productive cough and high fever. Her whiteblood cell count was 3200/ul (normal count 5000-9000/ul). 25%percent of her white cells were neutrophils (very low), 40% werelymphocytes (normal), and 29% were monocytes (elevated, normal 2 to8%). A serum test revealed that her IgG level was 35 mg/dl (normal600-1500 mg/dl), IgA was undetectable (normal 150-225 mg/dl) andher IgM level was 210 mg/dl (normal 75-150 mg/dl). A flowcytometric analysis of her peripheral blood cells revealed that allof her B cells were IgM+, IgD+.
- Provide a possible diagnostic for the patient.
