Compare and contrast the diseases epidermolysis bullosa simplex
(EBS) and sickle cell anemia. Include molecular level...
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Biology
Compare and contrast the diseases epidermolysis bullosa simplex(EBS) and sickle cell anemia. Include molecular level details forone similarity and three differences.
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AnswerSimilarities1Both occur due to arising mutations in thegeneIn Osteogenesis imperfecta OI mutations occur inCOL1A1 or COL1A2 genes Epidermolysis bullosasimplex EBS mutations occur in keratin5 gene KRT5 onchromosome 12 or on the keratin14 gene KRT14 on chromosome172Both Osteogenesis imperfecta OI and Epidermolysis bullosasimplex EBS are inherited in Autosomal Dominantmaner3In both OI and EBS Dental
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