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Comparing enantioselective carbonyl reduction using CBS reagent, and enantioselective biological reduction using an enzyme, what is an advantage and...

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Chemistry

Comparing enantioselective carbonyl reduction using CBS reagent,and
enantioselective biological reduction using an enzyme, what is anadvantage
and disadvantage for each?

Answer & Explanation Solved by verified expert
3.6 Ratings (455 Votes)
CBS advantages The CBS reduction has proven to be an effective and powerful method to reduce a wide range of different types of ketones in both a stereoselective and chemoselective manner disadvantages The presence of water in the reaction mixture has been shown to have a significant effect on enantiomeric excesses and thus the CBS reduction    See Answer
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