Consider cargo proteins that are destined for secretion to theextracellular space. Please predict where the cargo will end up(ex. in the cytoplasm, a specific organelle, transport vesicles,multiple places, extracellular space) for: (i) & (ii) Eachindividual condition; & (iii) The combination of bothconditions.
C.
(i) v-SNAREs on COPII coated vesicles are mutated to be unableto bind t-SNAREs
(ii) A transmembrane domain is added to the cargo protein.
(iii) Both
D.
(i) Receptors in the Golgi are mutated so they are unable tobind to cargo proteins.
(ii) COPI coat proteins are mutated so they are unable to bindto membranes.
(iii) Both
