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Describe how a point mutation in genomic DNA may be detected by MLPA in a single...

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Biology

Describe how a point mutation in genomic DNA may be detected byMLPA in a single tube. Highlight the critical elements of probesand primers used to detect a “wild type” and single nucleotidevariant. Ensure the role of enzyme(s) required for this assay areexplained.

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Ans MLPA identifies the deletionsduplications and helps in detection of known point mutations but not suitable for detection of unknown point mutation In the MLPA the Probes function is to detect the reference wild type sequence or the SNPpoint mutation sequence of interest As we know for detection of known point    See Answer
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