Logo
Home Study Material Contact Search
AI Chat FREE
  1. sciences
  2. biology
  3. describe how a point mutation in genomic dna may b

Describe how a point mutation in genomic DNA may be detected by MLPA in a single...

90.2K

Verified Solution

Question

Biology

Describe how a point mutation in genomic DNA may be detected byMLPA in a single tube. Highlight the critical elements of probesand primers used to detect a “wild type” and single nucleotidevariant. Ensure the role of enzyme(s) required for this assay areexplained.

Answer & Explanation Solved by verified expert
4.2 Ratings (630 Votes)
Ans MLPA identifies the deletionsduplications and helps in detection of known point mutations but not suitable for detection of unknown point mutation In the MLPA the Probes function is to detect the reference wild type sequence or the SNPpoint mutation sequence of interest As we know for detection of known point    See Answer
Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:
  • Unlimited Question Access with detailed Answers
  • Zin AI - 3 Million Words
  • 10 Dall-E 3 Images
  • 20 Plot Generations
  • Conversation with Dialogue Memory
  • No Ads, Ever!
  • Access to Our Best AI Platform: Zin AI - Your personal assistant for all your inquiries!
Become a Member

Other questions asked by students

Q

5 Maybelline recently introduced a high-end lip balm called BabyLips. The national target market...

Accounting
Q

Suppose we are running a Gas Chromatography for a mixture of standard alkanes (C5-C18) in hexane...

Chemistry
Q

Module 2 Programming Assignment – Battleship Refactor Refactor your Battleship drawing code from Module 1. Download the OO...

Programming
Q

• Impact of technology: 1) Evaluate how technology might affect your clinical specialization (Mental Health Counselor), including...

Psychology
Q

A. A disk of radius 0.15 m spins at a rate of 18 rad/s. What is...

Physics
Q

explain how to detect assignable causes of variation using probability paper

Basic Math
Q

Two point charges A q m and B 2q m2 are placed at rest at...

Physics
Q

T R U 42 171 2 1360 12 711 S mRS

Geometry
Q

PV PMT ORD IY CY 1 CY 1 DPP 1 i PF 1 NCY x...

Basic Math
Q

A fixed asset with a cost of $52000 and accumulated depreciation of $47,500 is traded...

Accounting
Q

Testin llc uses variable costing and absorption costing. Using absorption costing income statement, fixed manufacturing...

Accounting
Q

Jan. 3 Issued a check to establish a petty cash fund of $4,500. ...

Accounting