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Describe the function of scramblase in the ER and in the plasma membrane. Mention all relevant...

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Biology

Describe the function of scramblase in the ER and in the plasmamembrane. Mention all relevant enzyme characteristics necessary tosupport this function.

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The plasma membrane of cell and the ER membrane has an inner and outer leaflet In inner leaflet there is phosphatidyl serine PS phosphatidylethanolamine PE and phosphatidylinositol PI The outer leaflet has sphingomyelin SM and phosphatidylcholine PC Specific proteins such as flippases floppases and scramblases maintain this asymmetry of lipids in the plasma membrane via transbilayer lipid motion Flippases and floppases move the lipids to inner and outer leaflets of the plasma membrane Their functions require ATP The scramblases on the other hand maintain    See Answer
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