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Describe the histological changes that occur in patients with Zollinger-Ellison Syndrome. What is the etiology of...

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Medical Sciences

Describe the histological changes that occur in patients withZollinger-Ellison Syndrome. What is the etiology of the disorder?How does the etiology of this disorder differ from that ofgastroesophageal reflex disease? What protective mechanisms doesthe tissue employ to prevent the tissue damage observed indisorders mentioned above?

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Zollinger Ellison Syndrome is a gastrinoma Tumor that affects upper part of pancreas to produce gastrin leading to increased production of gastric acidhypersecretion ultimately causing peptic ulcer ETIOLOGY This can happen on its own or as a part of dominant syndrome called Multiple Endocrine Neoplasia Type 1MEN1The primary tumor is usually located in the pancreasduodenum or abdominal lymph nodes This is a    See Answer
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