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During vigorous exercise, how is skeletal muscle pyruvate dehydrogenase regulated to increase its level of activity? In...

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Biology

During vigorous exercise, how is skeletal muscle pyruvatedehydrogenase regulated to increase its level of activity?

In your response include metabolites that affect PDH kinase andtherefore the activity of PDH.

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3.8 Ratings (470 Votes)
During exercise the activation of pyruvate dehydrogenase in human skeletal muscle is regulated by three metabolites aIncreases in Ca2 bIncrease in free ADP c Concentration of    See Answer
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