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Enkephalins are morphine like substances produced in the body. Enkephalins presynaptically inhibit the release of neurotransmitter from...

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Medical Sciences

Enkephalins are morphine like substances produced in the body.Enkephalins presynaptically inhibit therelease of neurotransmitter from neurons that convey signals fromnociceptors in the skin to the spinal cord. Based on your knowledgeof the functional anatomy of a synapseandpresynapticmodulation at axoaxonic synapses, explain howenkephalins, and morphine, decrease perception of pain, whichoccurs at the level of the brain.

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Ans Enkephalins are small peptides that can serve as neurotransmitters in the brain Enkephalins act to attenuate substance P release in the dorsal horn of the spinal cord and inhibit afferent pain fibers Opiates inhibit transmission at sympathetic and locus caeruleus synapses Mechanism of action Enkephalin is also considered a neuropeptide which in the human body performs as an important signaling molecule in the brain Enkephalins are found in high    See Answer
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