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Evaluate the statements below, and select those that correctlyapply to the process of high throughput genome sequencing. CheckAll That Apply In the 4th step, the sequenced fragments arealigned, and the entire genome is computed using bioinformaticssoftware. In the 4th step, the sequenced fragments are aligned, andthe entire genome is computed using bioinformatics software. In thethird step, the amplified fragments are read and sequenced based onthe Sanger method. In the third step, the amplified fragments areread and sequenced based on the Sanger method. In the second step,the fragments bind to static probes and are amplified by PCR. Inthe second step, the fragments bind to static probes and areamplified by PCR. In the third step, gaps between contigs must beresolved to obtain the entire sequence. In the third step, gapsbetween contigs must be resolved to obtain the entire sequence. Inthe second step, each of the DNA fragments is engineered into aplasmid, and the plasmid is inserted into an E. coli cell toproduce a library. In the second step, each of the DNA fragments isengineered into a plasmid, and the plasmid is inserted into an E.coli cell to produce a library. In the first step, the DNA isfragmented and fitted with short DNA sequences designed to matchprobes in the second step.