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Explain in detail how the medullary osmotic gradient is generated and maintained and why the gradient...

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Medical Sciences

Explain in detail how the medullary osmotic gradient isgenerated and maintained and why the gradient is important forregulating water balance and urine volume

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Urea recirculates in the inner medulla building a stronger osmotic gradient It enters the interstitial space from the collecting duct following the concentration gradient created by the ADHsensitive water reabsorption Increased interstitial osmolarity pulls the remaining water from the descending structures Final concentration of urine in the collecting ducts rely on the medullary    See Answer
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