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For a physician, treating a biofilm infection in a patient poses a significant challenge compared to treating an infection with planktonic bacteria. This is due to the fact that ______.the biofilm likely contains several different species of bacteria living in a thick, extracellular matrix that cannot be treated by routine antibiotic therapyplanktonic bacteria and biofilm bacteria activate the same genesdespite being a thick layer, the pH remains constant throughout the biofilm making the deep layers hard to penetrateplanktonic bacteria secrete quorum-sensing proteins that interfere with the actions of the antibiotic
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