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Give a detailed description of the Ames assay including how it is performed, the basic principle...

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Medical Sciences

Give a detailed description of the Ames assay including how itis performed, the basic principle of how mutants are detected, whatgeneral types of mutations can be detected, and the advantages anddisadvantages of the Ames assay over more complex mammaliangenotoxicity tests.

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The Ames assay test is used to check whether a given chemical can cause any mutation to the DNA of the test organism It uses several strains of the bacterium Salmonella typhimurium that carry mutations in genes involved in histidine synthesis The bacteria are spread on an agar plate with a small amount of histidine This small amount of histidine in the growth medium    See Answer
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