How can you experimentally demonstrate that a specific GPCR
couples through Gi alpha subunit to inhibit...
80.2K
Verified Solution
Link Copied!
Question
Biology
How can you experimentally demonstrate that a specific GPCRcouples through Gi alpha subunit to inhibit adenylyl cyclaseactivity
Answer & Explanation
Solved by verified expert
3.9 Ratings (461 Votes)
When a GPCRbinds a ligand the ligand triggers a conformational change in the seventransmembrane region of the receptor This activates the Cterminus whichb then recruits a substance that in turn activatesthe G protein
See Answer
Get Answers to Unlimited Questions
Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!
Membership Benefits:
Unlimited Question Access with detailed Answers
Zin AI - 3 Million Words
10 Dall-E 3 Images
20 Plot Generations
Conversation with Dialogue Memory
No Ads, Ever!
Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!
