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How did MRSA become resistant to methicillin?mutation in a porin geneacquired a penicillin binding protein...

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How did MRSA become resistant to methicillin?mutation in a porin geneacquired a penicillin binding protein that had low affinity for methicillinmutation in a drug efflux pumpacquired a beta-lactamase that could destroy penicilin

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