How does a transgeneic mouse model overexpress LMO2? Explain the
process.
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How does a transgeneic mouse model overexpress LMO2? Explain theprocess.
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One of the causes of Tcell acute lymphoblastic leukemia TALL development is Overexpression of LMO2 It is suggested in LMO2overexpressing transgenic mouse models that accumulation of immature Tcell progenitors occurs in the thymus Additionally Lmo2 is not required for Tcell or Bcell development The Lmo2 protein has two Zinccoordinating LIM domains that are
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