Identify the major neurotransmitters and briefly discuss their
distribution in the nervous system.
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Identify the major neurotransmitters and briefly discuss theirdistribution in the nervous system.
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Neurotransmitter is a chemical substance that acts as a mediator for the transmission of nerve impulse from one neuron to another neuron through a synapse ACETYLCHOLINE Acetylcholine is a cholinergic neurotransmitter It possesses excitatory function It produces the excitatory function by opening the ligandgated sodium channels Source Acetylcholine is the transmitter substance at the neuro muscular junction and synapse It is also released by the following nerve endings 1 Preganglionic parasympathetic nerve 2 Postganglionic parasympathetic nerve 3 Preganglionic sympathetic nerve 4 Postganglionic sympathetic cholinergic nerves i Nerves supplying eccrine sweat glands ii Sympathetic vasodilator nerves in skeletal muscle 5 Nerves in amacrine cells of retina 6 Many regions of brain Synthesis Ach is synthesized in the cholinergic nerve endings Synthesis takes place in axoplasm and Ach
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