Imagine a genetic defect that affects embedded proteins within
the cellular membrane (assume that somehow this...
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Imagine a genetic defect that affects embedded proteins withinthe cellular membrane (assume that somehow this condition iscompatible with life). Which forms of cell membrane transport wouldbe affected by this disease, and which forms of cellular transportwould proceed unaffected? Be sure to include rationale for yourinclusion of each type of cell membrane transport in its respectivecategory.
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Alzheimers disease AD as a disorder of the plasma membrane Alzheimers disease AD is a common progressive degeneration of human brain structure and function resulting in a deterioration of mood behavior functional ability cognition and memory Globally 5 million new cases of AD are diagnosed annually with one new AD case being reported every 7 s In this country taking care of AD patients places a tremendous socioeconomic burden not only on unpaid caregivers but on our health care system as a whole The neuropathology of AD is highly variable and complex in its presentation and the greatest risk factor for AD is age Besides the appearance of neurofibrillary tangles at the root of the AD problem appears to be an upregulation in the generation of small toxic and highly amyloidogenic 42 amino acid amyloid beta A42 peptides that selfassociate ultimately clumping into proinflammatory and microgliaactivating senile plaques SP Interestingly all of the enzymatic machinery responsible for the generation of A42 and subsequent SP
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