In cell motility assays: a. Do we need to perform a cytotoxicity assay parallel with the motility...

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Biology

In cell motility assays:
a. Do we need to perform a cytotoxicity assay parallel with themotility assay? Why or why not?
b. If you know the IC50 value of the compound to be tested onthe motility assay, would you still need to perform thecytotoxicity assay? Why or why not?
c. Why do we use a DMSO control in cell-based drug assays? Forexample, do you need to include a DMSO control in every motilityassay? Why or why not?

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a Performing a cytotoxicity assay along with motility assay will give an idea of how cell motility is affected by the toxic reagents like reactive oxygen species or lethal drugs and helps to know the accuracy of the assay It gives exact See Answer

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In cell motility assays: a. Do we need to perform a cytotoxicity assay parallel with the motility...

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Biology

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