) In complex disorders, genetic susceptibility can be
supported by:
a) twin studies and adoption studies
b) genome...
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Biology
) In complex disorders, genetic susceptibility can besupported by:
a) twin studies and adoption studies
b) genome wide association studies
c) linkage analysis
d) whole exome or whole genome sequence studies
e) all of the above
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Susceptibility to complex human diseases such as diabetes and ischaemic heart disease arises from the complex interaction of environmental and host genetic factors Many human diseases are genetically complex Genetic susceptibility in such complex diseases can be supported by 1 Twin studies an adoption studies Monozygotic identical twins share the same DAN while dizygotic fraternal twins do not Studies of these twins provide an estimate of the relative contributions of shared genes and environment to disease phenotypes Carrier status for hepatitis B virus and the febrile response to Plasmodium falciparum will be similar in monozygotic twin pairs
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