. In the primary sequence of a protein, a valine is substitutedin place of a glutamic acid. Which of the following statements istrue? a. This is a transition from a non-polar amino acid to apolar amino acid. b. This will affect the secondary proteinstructure. c. This is a transition from a hydrophobic amino acid toa hydrophilic amino acid. d. This will have no effect on theprotein. e. This is a silent mutation.