Inborn errors of metabolism are disorders resulting from geneticdefects of metabolic genes that regulate energy metabolism.Although rare, there are 2 reported inborn errors of metabolismaffecting the process of gluconeogenesis. The first results in adeficiency of fructose-1,6-bisphosphate (FBPase) and the secondresults in a deficiency in phosphoenolpyruvate carboxylase (PEPCK).Both deficiencies present with the symptom of hypoglycermia (lowblood glucose) early in life during periods of fasting. a) What arethree main sources of glucose normally used to maintain euglycemia(normal blood glucose) in healthy individuals? b) Explain howdeficiencies in either FBPase or PEPCK can lead to this symptomspecifically during fasting. BE SURE TO REFERENCE THE SOURCES THATYOU LISTED IN PART A. c) The hypoglycemia associated with PEPCK isoften less frequent and less profound than in FBPase deficiency.Please explain this (hint think about the precursors forgluconeogenesis and how they are utilized within thegluconeogenenic pathway).
