Iron is an important item for the growth of microorganisms in a
pathogenic state in the...
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Biology
Iron is an important item for the growth of microorganisms in apathogenic state in the human body. Describe two ways in whichbacteria might attempt to obtain iron from human cells or tissuesfor their own use. Then, describe a way in which this bacterialiron-scavenging might be disrupted without harming the humancells/tissues in the process.
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Two ways in which bacteria might attempt to obtain iron from human cells or tissues for their own use are Nonheme iron acquisition systems It involve the production and secretion of highaffinity siderophores that are able to bind free iron ions and are able to extract iron from mammalian iron binding proteins and deliver it to specific outer membrane receptors or lipoproteins example of siderophoremediated iron acquisition Yersiniabactin system of Yersinia pestis it is able to extract iron from mammalian transferrin and lactoferrin proteins and deliver it to a specific outer
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