Know what ligand-gated ion
channelsare and their role in direct synaptic
transmission
Neurotransmitters:Â Â know the definition, and the
functions of...
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Biology
Know what ligand-gated ionchannelsare and their role in direct synaptictransmission
Neurotransmitters:  know the definition, and thefunctions of the following –
Acetylcholine (also know the toxins that disrupts this)
Norepinephrine
Dopamine and serotonin
endorphins
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Ligandgated ion channels are commonly known as ionotropic receptors These are a group of transmembrane ionchannel proteins which open to allow ions such as Na K Ca andor Cl to pass through the membrane in response to the binding of a chemical messenger such as a neurotransmitter These ligand gated ion channels bind neurotransmitters and open in response to the ligand binding These channels control the synaptic transmission between two neurons or between a neuron and a muscle One subfamily encompasses the Cysloop channels so named because of a large extracellular
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