List the stabilizing forces at tertiary level of proteinstructure. An enzyme containing the amino aspartic acid(pKa of the side chain = 3.65) and histidine(pKa of the side chain= 6) in the active (catalytic )site has an optimal activity at a pH of 5.0. What is the majorstabilizing force at the catalytic site? Using structures and 1-3complete sentences, predict and explain what is expected to happento the activity if the pH is increased to 8.
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