Look up the RPL4 gene in Drosophila melanogaster (fruit fly) inEntrez Gene.
(a) What is RefSeq accession number of the genomicsequence of the gene? What is the RefSeq accession number of thecorresponding mRNA sequence of the gene?
(b) Identify the same gene in Bos taurus (cattle).What is the RefSeq accession number of the genomic DNA sequence ofthe RPL4 gene in this animal? What is the RefSeq accession numberof the corresponding mRNA sequence?
(c) Using the Needleman-Wunsch algorithm, determinewhether the two genomic se- quences of the gene in fly and cow arehomologous. How do you know? Do the same with the correspondingmRNA sequences. Which of the two (genomic or mRNA sequence) Is moreuseful for drawing a conclusion regarding homology? Why does thattype of sequence lead to a higher percent identity? To answer thisquestion use the EMBOSS needle program with default parameters.
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