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Multiply in salivary gland and transform Metacyclic trypomastigotes Leave the midgut and transform Epimastigotes Transform in gut of tsetse fly and multiply Procyclic trypomastigotes Toetse fly takes a blood meal injecting trypomastigotes Tsetse fly stages Tsetse fly takes a blood meal injesting trypomastigotes CHayden McNeil LLC African sleeping sickness Trypanosoma life cycle Human stages Transform in bloodstream Bloodstream trypomastigotes 3 Multiply by binary fission in body fluids Diagnostic stage in blood T brucei cycle between two hosts vertebrates e g humans and the tsetse fly Infected flies transmit the parasite to humans when they bite their victims In the bloodstream the parasite undergoes structural changes and is carried to other tissues These organisms divide by binary fission and are transmitted to tsetse flies when the flies feed on infected vertebrates Trypanosomes are distinguished by a singular mitochondrion the kinetoplast located near the base of the flagella and by their elongated shape a distinctive flagellum and an undulating membrane The nucleus is also distinct and is located in a more central region of the organism Examine the prepared slide Draw the organism and label cellular structures where appropriat Note the pale circles surrounding the worm like organisms are red blood cells rypanosoma sp Q Do these trypanosomes infect blood cells Explain

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